Abstract: In order to select the good varieties of rice suitable for the environment of rice-fish symbiosis, 9 varieties of hybrid medium indica rice were selected as the test materials, including Yexiangyou 676, Yliangyou 5866, Jingliangyouhuazhan, Yliangyou 676, Wanxiangyou 111, Zhenyou 727, Zhongzheyou No.8, Nongliangyou 3135 and Shenliangyou 332. The yield and resistance of the tested varieties were investigated by using the single factor randomized block design under the environmental conditions of raising fish in paddy field. The results showed that the three varieties including Yliangyou 5866, Zhongzheyou No.8 and Zhenyou 727 had moderate growth period, good comprehensive resistance, high yield and good grain quality. Shenliangyou 332 and Jingliangyouhuazhan had better comprehensive performance in the environment of rice-fish symbiosis. Yexiangyou 676 had a moderate growth period, with high yield and good grain quality, but the rice false smut occurred seriously. However, the yield, quality and disease resistance of Nongliangyou 3135, Wanxiangyou 111 and Yliangyou 676 were general. According to the comprehensive performance of the tested varieties, Yliangyou 5866, Zhongzheyou No.8 and Zhenyou 727 were more suitable for the environment of rice-fish symbiosis, which could be promoted vigorously.