Abstract: The effect of different nitrogen regulation on the growth and yield of hybrid rice Jingfu 8 you 77 was studied in this paper, in order to provide scientific basis for the rational application of nitrogen fertilizer on Jingfu 8 you 77. By setting two levels of conventional nitrogen application (200 kg·hm^-2) and reduced nitrogen application (150 kg·hm^-2), as well as different ratios of base fertilizer, tillering fertilizer and earing fertilizer, the field experiments were conducted to compare the effects of different nitrogen regulation methods on the growth, development and yield of hybrid rice Jingfu 8 you 77. The results showed that:compared with the conventional nitrogen application, the yield of rice under the level of reduced nitrogen application was the highest (being 7 384.4 kg·hm^-2), with the ratio of base fertilizer, tillering fertilizer and earing fertilizer being 4.5:1.5:4, which was 2.4%-13.6% higher than that of other treatments, respectively. Under the level of conventional nitrogen application, the ear bearing tiller rate of rice was higher, and the tiller number increased, but the accumulation of dry matter was lower in later period, and the yield was lower. Under the level of reduced nitrogen application, the reasonable adjustment of the ratio of base fertilizer, tillering fertilizer and earing fertilizer could promote the occurrence of tiller number, improve the ear bearing tiller rate, benefit the accumulation of dry matter in late period, increase the grains per panicle, seed setting rate and thousand kernel weight, and finally increase the yield of rice.