Abstract: The effect of balanced fertilization of nitrogen, phosphorus and potassium on the yield increase of sweet potato Pushu 32 was studied in order to provide reference for the promotion of Pushu 32 in eastern Fujian. By taking Pushu 32 as the experimental material, the effects of different nitrogen, phosphorus and potassium on the yield of Pushu 32 were compared and analyzed by using the ″3414″ experimental method in the field. The results showed that different amounts of nitrogen, phosphorus and potassium fertilizer significantly affected the yield of sweet potato Pushu 32, among which nitrogen fertilizer had the greatest effect, followed by potassium fertilizer and phosphorus fertilizer had the least effect. The statistical analysis showed that there was a significant regression relationship between the fresh potato yield of Pushu 32 and the amounts of nitrogen, phosphorus and potassium fertilizer. When the ratio of the three elements was 1.00 ∶ 0.45∶ 1.46, that was, the pure nitrogen application rate was 128.55 kg·hm^-2, the phosphorus pentoxide application rate was 57.64 kg·hm^-2, and the potassium oxide application rate was 187.65 kg·hm^-2, the fresh potato yield was the highest, reaching 44 509.7 kg·hm^-2. The results of this experiment could provide scientific fertilization basis for the planting promotion of Pushu 32 in eastern Fujian.