Abstract: With the improvement of people's living standards and the change of consumption concept, the potato balls with the sweet potato as the main raw material was more and more popular among the young people. In order to screen the germplasm resources of special sweet potato suitable for the processing of sweet potato balls and study the best technological formula for the processing of sweet potato balls, a total of 145 sweet potato germplasms planted in Yangzhong Science and Education Base of Fujian Agriculture and Forestry University were used as the raw materials for the processing of sweet potato balls. According to the comprehensive sensory score, the special sweet potato germplasm resources suitable for the processing of sweet potato balls was screened out, and the orthogonal test of process optimization was carried out on the selected germplasm. The results showed that five sweet potato germplasms with the sensory evaluation scores greater than 80 were selected from 145 sweet potato germplasm resources, which were SP1, SP4, SP35, SP70 and SP87, respectively. The SP1 with higher score was used to carry out the best process of sweet potato balls research, and the best technological formula was cassava flour of 20 g, water of 6 mL and sweetening chrysanthemum of 0.10 g.