Abstract: In order to clarify the regulatory effect of exogenous salicylic acid（SA）on the waterlogging tolerance of Luffa acutangula Roxb seedlings, 0.5, 1.0, 1.5, and 2.0 mmol·L⁻¹ salicylic acid solutions were sprayed on the leaves of angular sponge gourd Jinfu 15 to study its effects on the growth and physiological metabolism of luffa seedlings underwaterlogging stress.The results showed that under flooding stress, the root length, plant height, and fresh weight of winged gourd seedlings were significantly lower than those of CK（non flooding+no external application of SA). After spraying exogenous SA, the decrease in agronomic traits decreased, The root length and plant height of seedlings treated with SA1.5 mmol·L⁻¹ increased by 19.0% and 12.3% compared to the flooded control, respectively; The fresh and dry weight of seedlings treated with SA2.0 mmol·L⁻¹ increased by 9.0% and 19.2% respectively compared with CK1. Flooding stress increased the content of membrane lipid peroxides in the leaves of seedlings, while SA treatment significantly reduced the content of MDA and H₂O₂. Compared with CK1（flooding+no external application of SA), the SOD and CAT activities of seedling leaves were highest in the SA 1.5mmol·L⁻¹ treatment, with an increase of 37.5% and 52.18%, respectively. The POD activity was highest in the SA 2.0mmol·L⁻¹ treatment, with an increase of 78.1% compared to CK1. By comparing the total weighted values of comprehensive indicators, the order of strength of each treatment in terms of flood resistance is as follows: SA1.5＞SA2.0＞SA1.0＞SA0.5＞CK1. Among them, the SA1.5mmol·L-1 treatment and SA2.0mmol·L-1 treatment are relatively close in terms of total comprehensive weighted values, indicating that these two treatments perform similarly in terms of flood resistance. The flood resistance of the other treatments SA1.0, SA0.5, and CK1 weakens sequentially. Overall, the effect of 1.5 mmol·L⁻¹ SA treatment is the best.