Abstract: To investigate the effects of different application rates of Tebeigai Soil Conditioner on acidic soil improvement and sweet potato yield and economic benefits, field efficacy experiments were conducted in Qiaoliu Village, Honglai Town, and Dongtou Village, Guanqiao Town, Nan'an City. The experiment included four treatments: conventional fertilization（CK）, conventional fertilization + 750 kg·hm⁻² of Tebeigai Soil Conditioner（T1）, conventional fertilization + 1500 kg·hm⁻² of Tebeigai Soil Conditioner（T2）, and conventional fertilization + 3000 kg·hm⁻² of Tebeigai Soil Conditioner（T3）. The effects of different application rates on sweet potato yield, economic benefits, and soil physical and chemical properties were studied. The results showed that in Qiaoliu Village, Honglai Town, the fresh weight of sweet potatoes in the T2 treatment significantly increased by 3,033.0 kg·hm⁻² compared to CK, representing a 17.77% increase. In Dongtou Village, Guanqiao Town, the T2 treatment increased yield by 1,130.0 kg·hm⁻², representing a 6.48% increase. The effects of the soil conditioner on soil pH and exchangeable calcium content varied by experimental site. In Qiaoliu Village, Honglai Town, the soil pH in the T2 treatment increased to 4.63, a significant increase of 0.25 units, and exchangeable calcium significantly increased by 41.5 mg·kg⁻¹. In Dongtou Village, Guanqiao Town, the soil pH in the T2 treatment increased to 5.21, an increase of 0.08 units, and exchangeable calcium significantly increased by 38.4 mg·kg⁻¹. In both locations, the T2 treatment achieved the highest economic benefits, with net output values increasing by 16.23% and 3.75%, respectively.