Abstract: Using rice straw and hybrid Pennisetum as the culture material of oyster mushroom, and then using the culture medium residues of mushroom to cultivate Chinese cabbage. The results showed that the yield of Pleurotus ostreatus cultivated with Pennisetum alopecuroides as culture material was significantly higher than that of straw, and the biological efficiency was 94.51%. The yield of Chinese cabbage was not significantly different from the cultivation with culture medium residues of mushroom from rice straw and Pennisetum alopecuroides.