Abstract: The investigation on the contamination status of Vibrio parahaemolyticus in the aquatic products sold in Fuzhou would prevent the occurrence of foodborne diseases caused by aquatic products and provide references for the departments of food safety supervision. 360 commercially available aquatic products in Fuzhou were collected randomly, and the isolation and culture of Vibrio parahaemolyticus were conducted according to the national standard (GB 4789.7-2013 Food Microbiological Analysis). VITEK 2 Compact was used for the identification of the isolated strains and the multiplex fluorescent PCR was used to detect the virulence genes. A total of 115 strains of Vibrio parahaemolyticus were detected among the 360 samples with the positive detection rate of 31.94%. Among them, the detection rate of fish was 31.67%, the detection rate of shellfish was 42.5%,and the detection rate of crustaceans was 21.67%. The detection rate of Vibrio parahaemolyticus in aquatic products collected from the farmer's market was significantly higher than that from the supermarkets(P=0.003<0.01, χ²=8.637). The positive detection rate of Vibrio parahaemolyticus was at its peak from July to September, while the positive detection rate was at a low ebb in December, January, February and March. The carrier rate of virulence gene tlh and was tdh was 100% and 29.57%, respectively. The aquatic products sold in Fuzhou were all contaminated with Vibrio parahaemolyticus to varying degrees. It was recommended to heat and cook thoroughly while eating to avoid the cross-contamination between different kinds of aquatic products and reduce the possibility of infection.