Abstract: Based on the requirements of national first-class undergraduate course in social practice for personnel training, and under the background of vigorously promoting the curriculum integrated with ideological and political education in various disciplines, the problems existing in the traditional innovation and entrepreneurship practice course were analyzed. It was proposed that the traditional practice teaching mode of innovation and entrepreneurship should be reformed in combination with the "Internet +" Innovation and Entrepreneurship Competition for College Students in China. With the goals of "promoting learning by competition, being led by competition, promoting teaching by competition, and promoting practice by competition", the ideological and political elements contained in the innovation and entrepreneurship education were organically integrated, and the good teaching results have been achieved.