Abstract: The adaptability of rice seedlings to cadmium (Cd) was explored in this paper, in order to provide theoretical basis for the prevention and control of heavy metals in rice. The effects of different cadmium concentrations on the plant growth, cadmium content and physiological indexes of rice seedlings and their adaptability to cadmium were studied by using the agar culture medium to simulate the wetland environment. The results showed that the content of cadmium in rice seedlings increased with the increase of the concentration of cadmium, and the content of cadmium in the root was much higher than that in the aboveground parts. When the concentration of cadmium ≥ 2.5 mg·L^-1, the inhibition of fresh weight, dry weight, plant height and root length of rice seedlings reached a significant degree. The concentration of cadmium in the agar culture medium ranged from 0 to 20 mg· L^-1, and the concentration coefficient reached the minimum when the concentration of cadmium was 10.0 mg·L^-1 and then leveled off; while the transfer coefficient increased first and then tended to be stable. In conclusion, the growth of rice seedlings was significantly inhibited when the concentration of cadmium ≥ 2.5 mg·L^-1, and the rice seedlings had certain enrichment and transport capacity to cadmium.