Abstract: In order to explore the best fertilization method for the planting of sweet pepper and improve the output value and yield of sweet pepper, by taking the high-quality sweet pepper variety Fuyu (35-613) as the experimental material, three fertilization treatments were set up, namely, the conventional fertilization (T1 treatment), water-fertilizer integration+water-soluble fertilizer fertilization (T2 treatment), and single application of base fertilizer (CK treatment). And the soil changes were monitored at the same time, in order to study the effects of different fertilization treatments on the growth traits, yield, output value and soil fertility of sweet pepper. The results showed that: Compared with the single application of base fertilizer (CK), the conventional fertilization treatment and the water-fertilizer integration+water-soluble fertilizer fertilization treatment could increase the fruit length and fruit weight of sweet pepper, and promote the fruit bearing and strengthening of sweet pepper. Among them, the treatment of water-fertilizer integration+water-soluble fertilizer fertilization increased the yield and net output value of sweet pepper on the basis of reducing the chemical fertilizer input, and the effect was the best. It could effectively improve the soil nutrients and alleviate the soil acidification, which was suitable for the promotion and application in field.